The agreement study is underway

We are measuring our output against the commercial 3D-QCA analyses in the validation cohort — minimum lumen diameter, reference diameter, %diameter stenosis and lesion length, case by case, reported as bias and limits of agreement.

This is the gate. Nothing downstream means anything until it passes, the physiology work included, and %stenosis stays a research output until it does.

The first findings are already negative in places: the pipeline under-reads where the lumen pinches to one or two pixels. That is what the study is for. When it reports, the result goes to the top of the publications page whichever way it comes out.